It really depends on the year, model, engine, tranny...they have all had their lemmons.
I personally love a Dodge. They are the ones I have had the best luck with. Our '06 3500 has been through Hell and back, still going strong. My old 94 2500 I sold to the ranch when we left it has over 300K hard miles on it. Snow and mud for 6 months out of the year. Dirt roads and not many highway miles pulling a loaded stock trailer.
I always post this pic, but I will put it up again....ol red...
2000 Ford F250 custom built at the factory for hauling. 178,000 miles and no trouble with the tranny. 7.3 diesel and it is loud. Have always owned Dodges before. Will still buy either one and just look for the best price.