They can be pretty mean. A friend of mine just had to go move some buffalo for a farmer because a buffalo killed his son.
These buffalo have been at our place for 3 years now. They arent tame by any means but they wouldnt come at you or anything.
We have 10 head and they are pretty different which is nice. Some of the bigger girls are slow and easy then theres a couple small ones that are pretty crazy. They have a way bigger flight zone than cattle so you have to really use space to control the speed your going. You will never outrun a buffalo and they will run till they die so you have to be smart when your working them so your horses don't get beat.