You get 1 personal item (think purse, briefcase, laptop bag) and one piece of carry on luggage.
Liquids can go in your carry on. But don't pack them in there. You will have to send them through the x-ray machine separately, not inside your bag. So keep them easily accessible and ready to pull out when you go through security. All liquids must fit into One, 1qt clear plastic Baggie. The individual liquid containers in your baggie cannot be over 3oz ea. Gels, pastes, anything not a solid qualifies as a liquid.
If you have liquids beyond those restrictions, you can pack them in your checked luggage.
Nothing sharp or pointy in your carry on. Someone shared the TSA restricted list already.
When putting a carry on suitcase with wheels into the overhead storage bin above your seat, point the wheels out towards the aisle. It helps to get the door shut. If it won't fit, they will check it with the regular luggage and you can pick it up in baggage claim.
Leave yourself lots of time. Better to be early than rushed.