08-07-2014, 03:35 PM
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Testing for the frame overo gene (also known as the OLWS or LWOS gene) can prevent a lethal white foal.
Lethal whites (or LWOS/OLWS) foals are created when you breed two horses who are positive for frame together. When you do this, you have a 25% chance of creating a lethal white foal.
Because white patterns can hide (one member has a mare with a small star as her only white, yet she tested positive for frame), it's important to test any horse you suspect of carrying frame before breeding.
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