Genetic Disease - would you?
 
 

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Genetic Disease - would you?

This is a discussion on Genetic Disease - would you? within the Horse Breeding forums, part of the Horse Breeds, Breeding, and Genetics category
  • Horrible genetic disorders
  • Arabian horses tested positive for pssm

 
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    07-29-2011, 12:34 PM
  #1
Green Broke
Genetic Disease - would you?

I just wanted to spark a general discussion about genetic disease and at what point do you consider it unethical to breed a certain animal? HYPP, HERDA, SIDS, Lethal White - there are so many to name, and what is acceptable for breeding and what is not?

For example, lethal white - it's so difficult to determine being as it's a color before it's really a "disease". Is it ethical to breed a frame horse to a non-frame horse, knowing the foal may inherit frame and could potentially pass it on one day? Or is it a shame to lose such beautifully marked horses when they CAN be responsibly bred?

Another example, someone recently imported a gorgeous Arabian stallion into our community. Back when I was still considering maybe breeding Zierra, I perked up for months before he arrived. When he finally arrived, it was revealed he was a CA carrier - a horrible, deadly neurological disease in Arabs. His owner did the responsible thing and stated NO Arab mare would be bred to him without CA negative testing, but is it ethical to breed him at all? For me, as a horse owner, I wouldn't even breed a non-carrier to him - for fear somewhere down the road, someone gets ahold of the potentially carrier foal, doesn't know a think about CA and breeds a CA positive foal because some disreputable breeder didn't bother testing their stallion or insisting CA negative only mares be bred to him.

But isn't it the same with lethal white? Shouldn't I also refuse to ever breed a frame carrier for fear someone will breed that horse and produce a lethal white?

And of course you have the discussion on HYPP, where even carriers are affected by this horrible disease.

What are the ethical grounds? What are YOUR opinions on genetic disease, how far should we go to eliminate it completely from our animals?
     
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    07-29-2011, 12:50 PM
  #2
Super Moderator
Quote:
Originally Posted by MacabreMikolaj    
I just wanted to spark a general discussion about genetic disease and at what point do you consider it unethical to breed a certain animal? HYPP, HERDA, SIDS, Lethal White - there are so many to name, and what is acceptable for breeding and what is not?

For example, lethal white - it's so difficult to determine being as it's a color before it's really a "disease". Is it ethical to breed a frame horse to a non-frame horse, knowing the foal may inherit frame and could potentially pass it on one day? Or is it a shame to lose such beautifully marked horses when they CAN be responsibly bred?

I have to admit I do not fully understand this particular genetical malfunction, BUT if I understand correctly there is a test and breeding can be done safely. If that is true then I think safe breeding should be allowed but only after testing. If that's not true then I think it's quite a risk.

Another example, someone recently imported a gorgeous Arabian stallion into our community. Back when I was still considering maybe breeding Zierra, I perked up for months before he arrived. When he finally arrived, it was revealed he was a CA carrier - a horrible, deadly neurological disease in Arabs. His owner did the responsible thing and stated NO Arab mare would be bred to him without CA negative testing, but is it ethical to breed him at all? For me, as a horse owner, I wouldn't even breed a non-carrier to him - for fear somewhere down the road, someone gets ahold of the potentially carrier foal, doesn't know a think about CA and breeds a CA positive foal because some disreputable breeder didn't bother testing their stallion or insisting CA negative only mares be bred to him.
Can't talk to this one, not educated enough.

But isn't it the same with lethal white? Shouldn't I also refuse to ever breed a frame carrier for fear someone will breed that horse and produce a lethal white?

And of course you have the discussion on HYPP, where even carriers are affected by this horrible disease.
This disease is an easy one. Only breed if the horse is tested NN. With the new rule changes we should see this disease start to dominish and probably drop way down within the next 15 years. (I don't think the harshest rules take effect until about 2020.

What are the ethical grounds? What are YOUR opinions on genetic disease, how far should we go to eliminate it completely from our animals?
Is there a test for HERDA?
     
    07-29-2011, 12:53 PM
  #3
Banned
Quote:
Originally Posted by farmpony84    
Is there a test for HERDA?
Yes there is.
     
    07-29-2011, 12:53 PM
  #4
Green Broke
Yes, a horse can be normal (N/N), carrier (N/HRD) and affected (HRD/HRD). I do believe, like most diseases, HERDA only affects affected horses and carriers are not physically affected.
     
    07-29-2011, 12:57 PM
  #5
Banned
Easy question for me to answer, as I am black and white on this issue.

I do not believe in knowingly breeding an animal, whether afflicted itself or a carrier, that has the potential of perpetuating a genetic disorder, and yes that includes H/N horses, HERDA carriers, SCIDS carriers and others. I don't condemn those that do (in the case of carriers), but to me personally, it is irresponsible. If a genetic issue can be eliminated by breeding it out, it should be...
     
    07-29-2011, 01:09 PM
  #6
Super Moderator
Quote:
Originally Posted by Faceman    
Uh, yes...
How come the "Uh"? I've only bred once and since I was breeding from the Impressive line all of my research centered around HYPP. I've never researched HERDA. Simple question.
     
    07-29-2011, 01:09 PM
  #7
Super Moderator
Quote:
Originally Posted by MacabreMikolaj    
Yes, a horse can be normal (N/N), carrier (N/HRD) and affected (HRD/HRD). I do believe, like most diseases, HERDA only affects affected horses and carriers are not physically affected.
Thank you.
     
    07-29-2011, 01:26 PM
  #8
Banned
They say that hetero HERDA horses have increased joint elasticity and some kind of excess cartilage as opposed to bone. Which gives them an advantage in cutting. But does it have negative effects as well? More research needs to be done, I'd say.

Would I breed an HYPP positive horse? Absolutely not. Wouldn't own one, either.

I wouldn't breed a PSSM positive horse, either. More people need to know about that disease and start testing. It's far more prevalent than people realize.

Would I breed a HERDA or OLWS carrier? Depends. I'd be far more likely to do the second than the first.

When you get right down to it, is it ethical to breed grays, with the risk of melanoma? Is it ethical to breed Appaloosas, with uveitis and nightblindness and increased risk of skin cancer?
     
    07-29-2011, 01:32 PM
  #9
Trained
I'm a (darn can't think of the word) Hard liner on this one, even though my actual experience with any of these conditions is zero.

To me with the ease and falling costs of genetic testing it should be easy, take HYPP as one example, take genetic material from foals and send them in with the registration papers, if they test negative sned them approved for breeding papers, if they test positive then stamp the papers not approved for breeding, any offspring will not be eligible for registration.

You wont wipe out the disease there will be the unethical and the byb;s who will breed anyway, but if you can't produce registrable foals then you remove the temptation to breed entirely without regard to the risk.

I know this wont be popular, but I would argue it would go a long way to wiping out these conditions over time.

The OLWS thing, I just don't get
     
    07-29-2011, 02:16 PM
  #10
Showing
Would someone mind explaining OLWS to me?
     

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