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Now this is weird...

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        12-07-2010, 11:01 AM
      #11
    Started
    No, it's not always due to chimerism. And brindle in dogs is a gene, not due to chimerism. And what about calicos?
         
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        12-07-2010, 11:15 AM
      #12
    Green Broke
    Sorry, it was from on of the threads linked in here:

    Quote:
    Originally Posted by Chiilaa    
    Interestingly, chimerism is also thought to account for male tortishell (calico) cats. Usually they are only female, since the colour genes are gender related, but rarely a male one will crop up. Most male tortishells are explained by people not recognising the colour correctly, or moles on the skin that can cause a similar pattern.
         
        12-07-2010, 11:58 AM
      #13
    Trained
    I was under the impression that male calicos are generally caused by them having more than one X chromosome. Their genotype is XXY, I believe it's called Klienfelters syndrome. They are generally sterile....

    http://www.ncbi.nlm.nih.gov/pubmed/1163864
         
        12-07-2010, 12:23 PM
      #14
    Green Broke
    Wow, who knew that genetics could be so complicated! That's interesting that male calicos have carry XXY and are sterile.
         
        12-08-2010, 01:57 AM
      #15
    Green Broke
    Quote:
    Originally Posted by MN Tigerstripes    
    I was under the impression that male calicos are generally caused by them having more than one X chromosome. Their genotype is XXY, I believe it's called Klienfelters syndrome. They are generally sterile....

    An animal model for the XXY Klinefelter's syndrome... [Am J Vet Res. 1975] - PubMed result
    The ones that are genuinely tortishell (calico) are either chimera or Kleinfelters, yes.
         

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