I have a friend that had a horse with COPD (we finally had to have her put down), and she had great success with Cough Free. The biggest reason that she had to be put down was because she finally got sick enough that she lost all of her weight, and no matter what we did, she wouldn't put any of it back on. She was outside 24/7, except at feed time, and then it was only long enough to eat her grain, and then leave. The horses had free access to 3 round bales, so she had plenty of roughage when you figure in the pasture as well. She just wouldn't put her weight back on, and had gotten to the point where she was always heaving, even during the winter, so we done what was best for her, and had her put down. Wanda had her for several years with good health, but the last couple she started going down hill no matter what we done. She tried everything to save that horse, and I ended up having to hold Wanda up as the horse went down. Her story is also a good example of "A free horse isn't really free!"