I can usually tell from the "feel" most silicone sprays leave on my hands. It's kind of an oily feel, but leaves an "ewwww" feeling at the same time. It just feels "chemical". Just not pleasant at all.
I really don't know how to explain it really, feels are different for everybody, but that's as close as I can get. If you use it frequently, it makes your skin feel dry too.
But maybe I'm just sensitive to it, because a lot of people seem to like it or they wouldn't still be selling it.