To start off, I've always read that you should NEVER mix Devil's Claw/Yucca together with Bute, within the same 24hrs. So that's what I've been doing.
Lacey has ERU[Moonblindness] and requires Bute during acute episodes. I like to switch her back to DC/Y during the 'resting' phase for daily pain because she seems to be really sensitive to Bute, and, after more than 3 days of Bute, she gets unbelievably grumpy.
However, this morning I fed her DC/Y before looking at her eyes [she wears a flymask 24/7 during the summer]. She JUST had an episode under 2 weeks ago and she's never had 2 episodes that close together so I just handed her some DC/Y before checking [never going to do that again, believe me].
But, of course, she's having a BAD episode. Her right eye is completely swollen shut, the pupil is REALLY open, and as the day has progressed, the tears coming of of her eye have changed from clear to white-yellow.
Bottom line, she needs 3grams of Bute asap to get that eye under control.
But I gave her .5oz of DC/Y this morning at around 10am and I would be giving her Bute at around 3pm, if I didn't wait until tomorrow.
So what do I do? Wait until tomorrow morning when it's been 24 hours and is "safe" to feed Bute, give her Bute now and say "to heck with the "no NSAID mixing" warning??
I am definitely calling the vet in the morning and she will be seen - two episodes in 2 weeks is absolutely not ok...but until then.
According to this question on Yahoo Answers, she should be ok.....but I trust you guys more than I trust Yahoo Answers!! Haha Devil's Claw and Bute? Can't use together? - Yahoo! Answers
Thanks a bunch.
ETA - she has no known history of ulcers. But she does get grumpy with longer term Bute usage [even very very low dosages], my gut says that perhaps she is prone to them...and that's really what is spooking me from saying "to heck with it"