We had a pack of coyotes kill a foal here about 20 years ago. Since then, we have not let any mares foal very far from the house. They have killed all of our chickens, ducks and geese and we tried to keep them several times.
They kill calves every year around here but are harder on sheep and goats. A lot of stockmen keep guard dogs or guard donkeys out with their stock.
Husband and son shoot several a year around here. Husband dropped one a few weeks ago. He was huge and had dog teeth that were 2 inches long. He has a 22.250 with a 12X scope. It gets them at a 1/4 mile.