Definately supplements if she isn't on any yet. We had my dad's horse on 4-flex, and it worked wonders. He was 35+ years old when we had to put him down because he colicked. But he too would have issues standing after he laid down to roll. We never got to the point where we had to help him up, but he definately struggled. Once he was up, he was absolutely fine. He would run, buck, kick, he was still jumping small cross rails, and was barrel racing, albiet slower than he was years ago when that was his job. We just made sure he got supplements every day, and on some of his worse days, we'd also give him a bute tab or two, and just walk him around the ranch. Fortunately here our winters don't get very cold, which I'm sure helped him out a lot, but it was just a lot of maintenance, making sure that he was as comfortable as we could make him, and keeping in contact with the vet, to make sure we were doing the best thing for him. I agree that as long as you can still help her get up, and she's fine once she's standing, she's not ready to go. When she's ready, she'll tell you. Good luck with her. Give her some hugs.