Genetic Diseases
 
 

       The Horse Forum > Keeping and Caring for Horses > Horse Health

Genetic Diseases

This is a discussion on Genetic Diseases within the Horse Health forums, part of the Keeping and Caring for Horses category
  • Quarter horse stallions genetic diseases
  • Hypp life expectancy

 
LinkBack Thread Tools
    07-27-2011, 11:37 AM
  #1
Super Moderator
Genetic Diseases

I thought it would be helpful to post known genetic disorders and post any information that might be helpful to forum members.

I borrowed the below information from a website (link pasted below)

Glycogen Branching Enzyme Deficiency (GBED) – Recessive. Found in some lines of Quarter Horses and related breeds. Always fatal in utero or within 4 months of birth. Results from lack of the enzyme allowing branching of glycogen (sugar units) in muscles and resulting lack of nutrients required for survival. Prevent by not crossing two carrier horses. A genetic test for GBED is in development by the University of California at Davis.

Hereditary Equine Regional Dermal Asthenia (HERDA), Formerly called Hyperelastosis Cutis (HC) – Recessive. Found in some offspring of the Quarter Horses stallion “Poco Bueno.” Average life span is two-four years. Skin layers separate due to collagen defect, and horses cannot be ridden. Prevent by not breeding two carrier horses.

Hyperkalemic Periodic Paralysis (HYPP) – Dominant. Genetic mutation of sodium channel in muscle membranes that results in zero to severe muscle symptoms and possible death from heart failure. All affected horses trace back to the Quarter Horse Stallion “Impressive.” AQHA registered horses have a designation of N/N for normal, H/N for single gene and H/H for both mutated genes on the registration papers. Prevent HYPP by testing all Impressive-bred horses and not breeding horses with H/N or H/H designation. Management of affected horses is possible with medication from a veterinarian and/or carefully balanced low-potassium rations.

Recurrent Exertional Rhabdomyolysis (RER) – Dominant. Genetic form of tying-up or muscle damage and stiffness usually found in young, excitable Thoroughbred racing fillies. Management is possible by reducing starch and adding fat and following carefully managed exercise program. Diagnosis is possible with muscle biopsies.

Overo Lethal White Syndrome (OLWS) –- Recessive. Disorder of Paint and Pinto horses resulting in pure white color and incomplete formation of the digestive tract. Always fatal in utero or within hours of birth. Prevent OWLS by not crossing two horses with Overo (one form of pinto spotting) coloring or breeding. A test for the Overo gene is available from the American Paint Horse Association.

Polysaccharide Storage Myopathy (PSM) – Dominant. Genetic form of tying-up with muscle damage and inability to move, usually found in Quarter Horses, Draft Horses and crossbreds. Horses make and store abnormal muscle glycogen and cannot tolerate dietary starches and sugars. Horses with PSSM can be maintained with low-starch and low-sugar rations and precise exercise protocols. Diagnosis is possible with muscle biopsies.

Severe Combined Immunodeficiency (SCI) – Recessive. Lack of normal immune function in Arabian Horses. Usually fatal early in life. Prevent by not breeding two carriers. No genetic test at this time.

Information taken from the below website:
http://www.admani.com/allianceequine/techbulletins/InheritanceOfGeneticDisorders.htm
     
Sponsored Links
Advertisement
 
    07-27-2011, 12:00 PM
  #2
mls
Trained
Quote:
Originally Posted by farmpony84    

Severe Combined Immunodeficiency (SCI) – Recessive. Lack of normal immune function in Arabian Horses. Usually fatal early in life. Prevent by not breeding two carriers. No genetic test at this time.

Information taken from the below website:
http://www.admani.com/allianceequine...cDisorders.htm
Many Arab stallions will post on their advertising SCID clear.

Maybe no genetic testing but it is most certainly preventable.
     
    07-27-2011, 05:20 PM
  #3
Banned
Another: Cerebrellar Abiotrophy in Arabians
http://www.arabianhorses.org/educati...phy_Review.pdf

Also: Lavender Foal Syndrome
Lavender Foal Syndrome - Wikipedia, the free encyclopedia
     
    07-27-2011, 05:30 PM
  #4
Showing
Subbing...
     
    07-27-2011, 05:50 PM
  #5
Foal
This is some great info! Does anyone know of any good books out there with this kind of genetic info?- Like even a Vet Text book kind of thing?
     
    07-27-2011, 05:59 PM
  #6
Weanling
This is very interesting! If I'm really honest, I don't think I've heard of any of these (except I have heard of a similar case to the overo lethal white, but in New Forest Ponies, I think there were a couple of cases in 2009 or something)

Very interesting post!
     

Quick Reply
Please help keep the Horse Forum enjoyable by reporting rude posts.
Message:
Options

Register Now

In order to be able to post messages on the The Horse Forum forums, you must first register.

Already have a Horse Forum account?
Members are allowed only one account per person at the Horse Forum, so if you've made an account here in the past you'll need to continue using that account. Please do not create a new account or you may lose access to the Horse Forum. If you need help recovering your existing account, please Contact Us. We'll be glad to help!

New to the Horse Forum?
Please choose a username you will be satisfied with using for the duration of your membership at the Horse Forum. We do not change members' usernames upon request because that would make it difficult for everyone to keep track of who is who on the forum. For that reason, please do not incorporate your horse's name into your username so that you are not stuck with a username related to a horse you may no longer have some day, or use any other username you may no longer identify with or care for in the future.

User Name:
Password
Please enter a password for your user account. Note that passwords are case-sensitive.
Password:
Confirm Password:
Email Address
Please enter a valid email address for yourself.
Email Address:

Log-in

Human Verification

In order to verify that you are a human and not a spam bot, please enter the answer into the following box below based on the instructions contained in the graphic.


Old Thread Warning
This thread is more than 90 days old. When a thread is this old, it is often better to start a new thread rather than post to it. However, If you feel you have something of value to add to this particular thread, you can do so by checking the box below before submitting your post.

Thread Tools

Similar Threads
Thread Thread Starter Forum Replies Last Post
Strangles+other diseases?? spudicus Horse Health 1 02-03-2011 10:26 AM
Tick Diseases zurmdahl Horse Health 2 06-03-2009 07:43 PM
Equine Diseases of Concern shmurmer4 Horse Health 5 03-15-2009 12:59 AM
Infectious Diseases Meg Horse Health 5 11-05-2008 10:57 AM
Tropical Diseases in Horses??? ChrissyBz Horse Health 8 05-27-2008 02:18 PM



All times are GMT -4. The time now is 04:59 AM.


Powered by vBulletin® Version 3.8.5
Copyright ©2000 - 2014, Jelsoft Enterprises Ltd.
Search Engine Friendly URLs by vBSEO 3.6.0