I do have a question about the injection site being swollen though. Ricci's isn't that bad, maybe ping-pong ball sized. Gracie's though, is about as big as my hand, or an oblong softball. Gracie did get poked twice, which is part of why hers is so much bigger. I have been cold-hosing Gracie's site to help, but I was wondering about a medication of some kind. My options are Equi-Spirin [horse asprin], Bute, A Tri-Hist granule anti-histamine, and Benadryl. What would be best? Should I give her an anti-histamine because it a reaction, or a painkiller and anti-inflammatory because it's tender and swollen? The Tri-Hist stuff is my friend's, perscribed by a vet, so it's stronger than benadryl, at least I'd assume. I gave Gracie 3 Benadryl this morning, and Ricci 6 of them. They each got a dose of Equi-Spirin last night, and it helped some. I don't know. What should I give them!? Lol.