Hello this is Kerri and I have one very old very jumpy and very huge Quarter Horse mare that is desperately in need of dental work but she has had a negative reaction to a tranquilizer in the past as in it had the opposite effect!! NOT GOOD! She also does not react well to a twitch! Does anyone know if this drug Dormosedan is a safe and reliable tranquilizer? I may have spelled that incorrectly sorry but I really NEED to know. Any help will be very appreciated!