I don't think that your friends horse has reached the point yet where risks are going to kick in so probably no need to worry yet though something to counteract the risk of stomach ulcers would be a good idea
You don't mention if the horse has been on antibiotics but if not its possible that there is some infection going on that's getting into the bloodstream and affecting the kidneys
I would have some bloods taken if only to rule out anything
1Likes