L-Thyroxine for laminitis? - Page 5

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L-Thyroxine for laminitis?

This is a discussion on L-Thyroxine for laminitis? within the Horse Health forums, part of the Keeping and Caring for Horses category
  • Previcox use with laminitis
  • Prevacox for laminitis

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    11-19-2012, 10:50 AM
Green Broke
Oops double post, sorry.
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    11-19-2012, 10:52 AM
It's not really off topic, considering what I just read last night on another forum about a new drug for laminitis. It's a painkiller/anti-inflammatory without the nasty side effects of bute. What caught my eye was that researchers had different set ups, treated different symptoms at a time, and not one single horse was sound afterwards, new drug or not. Some of the treatment regimens made the horse better for a while, just to have another, worse flare -up. Goes to show you how complex a condition it is.
My mare, after her vaccine, developed COPD, desperately needed cortisone, but we couldn't do it, since it can cause laminitis. I eventually lost her to COPD, her laminitis being in check.
If I would have known what I know now, she still could be alive.

Makes me wonder if it wouldn't be better to come back to nature and let horses live like horses, let them become strong on their own, without much interference from certain standard treatments. We know that there is resistance to certain drugs, mainly from overuse, and slowly slowly minds change on deworming, for example.
Not to say a veterinary treatment has it's place, by all means, but sometimes less is more...
With that in mind, what my neighbor does is absolute natural, and he doesn't have laminitic horses, even tho they are quite fat in summer. It seems to balance out with the meager winters and constant movement.
Some people might call what he does neglect, for sure, I was the first to do so, when I saw it. But it for sure made me think.
These horses eat native grasses, some weeds, lick the soil in certain spots, travel a lot between good food and the water source, are exposed to the elements, heat being the worst, not a single tree in pasture. What do we do? Designer hay, highly nutritious, grain, turnout limited, wrapped in blankets......
I've decided to not up my horse's hay this winter, so my blimp can downsize a little, and what my mare might be lacking I rather make up with alfalfa pellets. I, due to not having plain grass hay available, got oat, 3-way, orchard and a little alfalfa, for diversity, have calculated the amount of each needed(they compliment each other nicely, btw), give a ration balancer, a little less than recommended because they get a lot out of the hay alone, salt and water. Out 24/7, shelter, which they use only to get away from the bugs. Blimp is already a bit trimmer
    11-19-2012, 10:55 AM
Green Broke
Is it previcox (equioxx)?
    11-19-2012, 11:06 AM
Originally Posted by spookychick13    
I definitely don't think it was coincidence that his episode started after the shot. How could it be?

It sucks though, since Brandon is only 18, I do ride him on trails and trailer him around. :/ Then again, who knows what his feet are going to be like after this?

A very good friend of mine who now lives out of state suggested Soft Ride boots and Farrier's Formula Double Strength.
With the right trim, his feet should be fine.
Farrier's formula will help growing nice strong feet. But balanced nutrition and the Omega Horseshine (love that stuff!), will do the same.
For boots, I was told by several people that certain brands fit certain hoof shapes better than others. That's why I suggested asking loosie, she has more experience with that, being a barefoot specialist.
With him being trailered out a lot, some vaccines are necessary. But it might be a good idea to not use the multiple ones, rather like flu and tetanus, then a couple of weeks later rabies, and so on, as to not overwhelm his system.
    11-19-2012, 11:09 AM
Originally Posted by spookychick13    
Is it previcox (equioxx)?
I didn't read the article about it, only the discussion around it, but it's possible. Tho, Equioxx is not that new anymore.
    11-19-2012, 11:15 AM
Green Broke
No, but people use previcox off label because it is cheaper (it's for dogs). I thought perhaps that is what they were referring to.

I worked as a small animal vet tech for years. :)
    11-19-2012, 11:22 AM
I'll try to find the thread and read the article
    11-19-2012, 12:42 PM
Super Moderator
Toxins in the bloodstream can cause laminitis which is why things like Lymes can trigger it and the small amount of toxin in the shot your horse had could have tipped him over the edge. The problem there is that if such a small amount that they use in a shot to maintain immunity could do that how badly is he going to be affected if he gets the real thing?
All horses react in different ways which is what makes laminitis such a difficult complex thing to deal with
Its been long established that steroids will cause a laminitis attack and as they suppress the immune system there has to be a connection with that and horses with IRS having a compromised immune system probably because Insulin production is essential for enabling glucose and glucose is vital for cell renewal and defence against infections and IRS horses don't produce effective insulin as for some reason they've developed an over active response where they produce way more than they need but it doesnt work properly
There are tons of papers on these things and unless you have a scientific brain they can send you on information overload!!!
The mare I have that is IRS is 21 - She is also slightly arthritic and has good and bad spells of that from time to time and I then have her on Previcox for quite long periods to keep her comfortable. Its never caused her to have a laminitis attack. I had her on Naproxin prior to that and again - no laminitis but it did cause ulcers.
    11-19-2012, 12:57 PM
Here is the link:
Futurity.org – New inflammation drug may spare horses

For the whole thread, which has tons of info and links, please PM me
spookychick13 likes this.
    11-19-2012, 01:06 PM
Super Moderator
Originally Posted by deserthorsewoman    
Here is the link:
Futurity.org New inflammation drug may spare horses

For the whole thread, which has tons of info and links, please PM me
Unfortunately the drug still hasnt gotten into the clinical trials stage yet and that can mean 4 years to just get it into the registration process and it could fall at any hurdle on the way there which happens a lot - my husband is a Global Head of R&D and so many really good products get dropped because of small problems that crop up or the costs of research & production outweigh the potential profits - which is all the big Pharma companies are interested in.

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