OspC – has been found to be a valuable indicator of early infection with B. Burg- dorferi. Antibodies to OspC can be detected as early as 3 weeks after infection. Anti- bodies to OspC start to decline after 7-11 weeks and become undetectable by 4-5 months after infection 12.
OspF – is an indicator of chronic infection. Antibodies to OspF are detectable by 5-8 weeks after infection and are maintained at high levels afterwards. Researchers at Cornell observed a very high agreement between antibodies to OspF and C6 as robust markers for infection 12. Horses with positive antibody values to OspF and negative antibody values to OspC are considered to be infected with B. Burg- dorferi for at least 5 months
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