05-02-2010, 11:08 AM
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Without seeing the lesions, what you are describing sounds like an eosinophilic granuloma. These can be caused from a number of things including insects and direct trauma (such as that from saddle fit issues).
Here is the description from merck......In horses, the disease has been termed equine eosinophilic granuloma with collagen degeneration, nodular necrobiosis of collagen, and collagenolytic granuloma. The lesions are nodular, nonulcerative, and nonpruritic. They often are found in the saddle, central truncal, and lateral cervical areas and may have a gray-white central core. Older lesions may become mineralized. Both insect bites and trauma have been suggested as etiologies, although the occasional onset during winter in cold climates and in noncontact saddle or tack areas suggests multifactorial causes. Histology reveals multifocal areas of collagen degeneration surrounded by granulomatous inflammation containing eosinophils. Thus, histologically, this lesion is similar to eosinophilic granuloma of cats and dogs.
In horses, solitary lesions may be treated with systemic antibiotics, surgical excision, or sublesional corticosteroid injections. Mineralized lesions require excision. Triamcinolone acetonide (3-5 mg/lesion) or methylprednisolone acetate (5-10 mg/lesion) is effective. No more than 20 mg triamcinolone acetonide should be administered sublesionally because of the potential to induce laminitis. Horses with multiple lesions may be treated with oral prednisone or prednisolone at 1.1 mg/kg, sid, for 2-3 wk. In horses with recurrent lesions, intradermal allergy testing, particularly with insect antigens, is recommended. Hyposensitization and insect control can be palliative in some cases.
I generally treat with corticosteroid injections, however, I have also had some lesions resolve by washing saddle pads, cleaning the areas with a dilute betadine solution, and increasing padding.
It would be wise to have your vet out to assess the lesions to be able to provide the most appropriate treatment to get them resolved.