Trouble getting up?

I would say call the vet, could sound like EPM/lyme disease. She would know best (your vet)

The only time I have seen a horse do this was because he had a broken hip (from over tranq'ing & falling in a vet clinic in their stockracks, new vet right out of university, nice huh?). It got worse & worse, he was kept at my daughter's, she would call us to help him up. We eventually had to set him free to run in the clouds. By the way, it was the chiropractor that diagnosed the broken hip, not the negligent new vet.

Has it been really hot in your area? Maybe the heat is getting to her? As far as EPM goes...its not something to mess with...if you have the slightest suspicion that EPM could be an issue, then get a vet out ASAP. I have dealt with it in the past and am dealing with it once again and it is a horribly debilitating disease that can push your horse downhill so fast. Both cases of mine have started out with different symptoms and the sooner its caught the better. You also have other neurological diseases that could cause the same symptoms....west nile, EHV1.

With any symptoms that could even remotely point towards diseases like those, a vet call sooner rather then later is your best option.

Waresbear, that's so awful :( Poor horse.

OP, please keep us updated and tell us what the vet says when they come out tomorrow. In fact, if I were you, I'd call back and ask them what their backup vet number is, because they should always have someone for emergencies. Horses don't know if it is 4th July or not haha, and this sounds pretty serious. Best of luck!

Tonight I was stretching her, and I'm thinking it's an adjustment that's needed. On her left hip, she was much more guarded with it. Or her hocks may be a bit stiff?
I've researched about every neuro thing you can imagine. And she isn't fitting anything it could be. And she's vaccinated on everything. She isn't sore or striding funny.
But either way, she's getting checked.
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So I'm not ruling it out, I'm just trying to not jump to conclusions. Because her pelvic area needs adjustment occasionally.
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Don't rule out EPM.

A friend of mine had a younger reiner who was having issues spinning in one direction -- he would just lay down. After many, many chiropractors, injections, etc. an osteopath realized that he had EPM. They tested him, he came back positive, and them put him on Marquis.

He never had any other symptoms of EPM.

His only symptom? Wow..
Well she isn't unbalanced though when she moves at all. She's extremely coordinated. But I'll keep it in mind for sure.
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Or even a selenium deficiency? That can link neuro stuff occasionally.
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My questions, if I may:

How old is she?

No previous injury you are aware of?

How long does it take her to get up?

Once she's up, how does she stand and move?

Is she lying down more than normal?

Diet:

How is her water, salt and mineral intake?

What type of diet does she have, and is her weight ideal for her age and breed?

Vaccines:

Have you noticed whether these incidents have coincided closely with vaccinations given? If you think there's a link, you may want to stop the vaccines and put her on a holistic cleansing/detox program.