I recently purchased this and decided not to use it. I've read that larger doses of Glucosamine could possibly cause problems in a horse who has had laminitis before, and I'm afraid to take any chances. He has been on Corta-Flx and has done Ok with that and BL Solution, so I'll probably just keep him on those and not try any injections. Adequan did not help him at all last year and that's why my vet suggested the Pentosan. I just ordered the wrong Pentosan and likely can't return it. Rather than keeping it around, I wanted to see if a needy horse rescue could use it.