After riding a head-shaking trekking pony who didn't listen to the bit at all, and who had neither brakes nor steering despite my best efforts, my hands were so sore. It was blissful to get back onto the well-schooled horse I ride in lessons!
I have different sets of calluses xD The tips of my fingers aren't that sensitive because of constant typing, and during term-time I build up pen calluses from writing. Last month I was playing some guitar after not having played in, oh, a year or so - the next day I actually had blisters on my fingers. After our holidays in the Lake District, I have calluses along the skin between thumb and forefinger and heel of my hand, from my kayak paddle - though I wear cycling gloves to stop blisters - and I tend to get ones in similar places from lots of sailing xD Finally, the sides of my feet toughen up a bit from dancing, though I must admit that the break from that is finally giving my toes a chance to recover from the mashing they so often get!
If you believe everything you read, better not read.