Smaller vehicles CAN work for pulling a 2 horse trailer...the problem comes when trying to stop with a smaller truck (s-10's, dodge dakota's etc) They have the muscle to pull it but you need to have a truck that can STOP it too.
I suggest for a 2-4 horse trailer, at least a 1/2 ton full sized truck. (this includes full size suv's as Suburbans/Tahoes(chevy/gmc) and Excursions/Expeditions(ford).)
I would also have trailer brakes for anything larger than a 2 horse trailer.
I air on the side of caution when hauling live animals. I have hauled a heavy car trailer with our Jeep Cherokee....but as I said earlier, a heavy trailer will push around a smaller vehicle.
What kind of trailer do you have and how many horses are you transporting??? That would help us make better recomendations.