Originally Posted by themacpack
My concern is more the fact that different species' systems process different chemicals in different ways - ie the fact that caffeine can be highly toxic to many common pets. Yes, again, it's perspective in regards to the size of most common pets vs. large animal such as horse - but that is more where my thinking goes is how the horse's system will process those ingredients and whether or not there would be adverse health effects.
I did look that up, caffeine is a banned substance in a lot of competitions. Most studies do show that yes it does effect them, but not as bad as you'd think at a lower dose. The one study I noted had horses being given doses of 4mg/kg IV. Meaning they were being given 4mg of caffeine intravenously-different than orally much more potent- per Kg of weight and had no lasting effects.
So...let's say a 1000lb horse = 454kg roughly. So in the experiment those horses were getting 1816mg of caffeine and had 1/2 of the drug in the blood stream 18 hours later and no detectable drug 48 hrs later. Which is why I said 80mg by mouth probably didn't effect the horse very much