For me, the standout is the Beast of the East, the
Old Dominion, which takes place in Orkney Springs, VA in mid-June. This AERC ride offers 25, 55, and 100 mile distances.
Other AERC rides in VA include
No Frills, which is in Star Tannery, VA in the end of April. It offers 30 and 55 mile distances.
Virginia Highlands Challenge, which is at the end of August (though hasn't hit the official calendar for this year yet), happens over 2 days in Ivanhoe, VA. It offers 30 and 50 distances both days. In October is
Fort Valley, which takes place over 2 days in Fort Valley, VA. It offers 30 and 50 miles distances both days.
I have not had the pleasure of riding AERC events in TN, KY, or NC yet, but I know they definitely have them. Check out the
AERC calendar for the current rides (but know rides are still being added, so the list may not be complete right now).