Cushings and Seizures???? - The Horse Forum
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post #1 of 6 Old 04-27-2015, 09:38 PM Thread Starter
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Exclamation Cushings and Seizures????

Disclaimer: the vet knows about the situation. I am posting this for whatever similar situations y'all know about that could provide some insight.
Whats going on:
Shetland/welsh pony mare, early/mid twenties. Recently she has been diagnosed with Cushings disease and has been promptly put on 'the pill' there are no mysteries there. The unusual thing is that twice now she has appeared to have a seizure or stroke. The first time I was not there to witness it but today I was.
Symptoms of 'incident 1': (as told by BO's husband) She appeared wobbly and began to chase her tail and moved 'like she was a windup toy' It looked like she was blind because she ran through the fence (electric) and straight into a trailor. When the episode was over she stood still like she was exhausted.

The vet who came out two days later for another horse told us that that sort of thing goes along with Cushings and should go away with 'the pill' (which she gave us that day to give to her)

Incident 2: I was feeding lunch and as I was walking back from the barn I peaked in her stall and noticed that her legs were twitching. So I stopped and watched. The twitches became more violent and traveled up her body till she was unstable and splayed her legs to stay upright. At this point I took her grain mash from her because I was afraid she'd choke. Then she started spinning. It was like she could not stop moving and her hind legs looked like they were going to give out on her. She moved jerkily exactly like a windup toy. She made it out of her stall and into her paddock where she ran around in circles with the same jerky motion. She eventually stopped. She went back in her stall. I started to take her pulse and her whole body went rigid when I touched her. I couldn't get a good count but her pulse was like a bird's. I called the BO's husband and as the phone was ringing she started twitching again and the whole process repeated itself. Both 'waves' lasted about two minutes from the beginning of the twitching to the end.

Any insights?
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post #2 of 6 Old 04-27-2015, 09:56 PM
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When the tumor gets too large, it can cause neurological symptoms , and the Pracend only controls the effects from excess hormone production

Here is some info. I had to put my gelding down, once her showed hind end weakness. The medication is not going to shrink that tumor

In the advanced stages of the disease, severe neurological problems can occur if the pituitary gland becomes big enough and causes compression in the brain. Symptoms of compression include ataxia (uncoordinated movement of the limbs), fever, hyperventilation and possibly recumbency leading to death. If treatment is not provided—and sometimes even if it is—the pituitary gland gets larger, the immune system weaker and the body condition worsens to the point of real debilitation for the horse. These horses look and act very old. Their hair coats are extremely long, sometimes several inches long, and very wavy. They breathe heavily and sweat in their stalls and seem extremely lethargic. They might start to sway when walking, and in the most extreme cases get to the point where they can’t get up.
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post #3 of 6 Old 04-27-2015, 10:22 PM Thread Starter
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Dangit. everything you mentioned sounds exactly like her. I grew up on this pony. Thanks for the insight though. This is her when I was in the 7th grade. She was the horse that taught me to fall and get up running:
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post #4 of 6 Old 04-27-2015, 10:46 PM
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Go to Equine Cushing's and Insulin Resistance Group Inc., read all there is about Cushings, sign up on the ecir yahoo group and ask there. You will get answers. Prascend dosage might not be enough, diet not quite right, whatever it is/ could be, you'll get an answer there.
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post #5 of 6 Old 04-27-2015, 10:49 PM Thread Starter
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DesertHorseman- Thanks. I don't know much about Cushings (as you've probably guessed) I will definitely do that.
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post #6 of 6 Old 04-27-2015, 11:07 PM
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It might be a little overwhelming first there is A LOT of info, a lot of things to do, change and think of, testing needs to be done, dosage adjusted, diet changed. But it will be well worth it. This group has been operating for 14 years, with over 12000 members, so they definitely know what they're talking about. Keep us updated, please
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