Depo Shots - The Horse Forum
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post #1 of 6 Old 12-23-2013, 03:23 PM Thread Starter
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Depo Shots

Hi everyone. I need further clarification about the depo shot used in mares. I've been having diarrhea issues with my horse, and I posted a thread on that a couple weeks ago. Some wonderful people suggested that since the diarrhea seems to come and go in cycles, that it may be hormone related. She's on depo, so I thought that hormones can't be the problem. Well, for the second time in less than two weeks my mare has shown the classic signs of being in heat. But she's on depo. How does that work? When I spoke to the barn manager, who's mare is also on depo, he told me that his mare did the same thing a few weeks ago. I got the bottle of depo in February last year from the vet. He said the bottle should last about a year, although its expiration date on it is 5/2013. The management at the barn gives it to her. Her most recent shot was last Thursday. And today she was showing signs of being in heat. I realize it could be that the batch is just expired and is no longer working, but am wondering about the long term effectiveness of it even when not expired. Thoughts?
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post #2 of 6 Old 12-23-2013, 06:13 PM
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It is regarded as the less reliable steroid option for controlling heat cycles. Its possible that the medication is out of date and less effective. That is somewhat unlikely as some research is suggesting that these drugs are viable long after their expiration dates. That said, I would want to use an in date drug in my horse. Have you looked into marbling your horse? Is her heat cycle really dangerous?
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post #3 of 6 Old 12-23-2013, 06:35 PM Thread Starter
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Well, she's no picnic during her cycles. I've heard of the marbles. How much would that even cost? As far as the depo not working, she's in heat, but she's not acting like she is. She's showing the signs, but not the usual bird-brained behavior. I'm thinking about seeing how she behaves without the depo. I'm hoping she was just going through an extremely hormonal year and is settling down now.
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post #4 of 6 Old 12-23-2013, 06:53 PM
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The only shots I have ever used on my mares have been testosterone. It was fairly cheap, and easy. Hmmmm, just like the mares, lol!! I used it because the Pinto mare in my avatar has a bloody discharge, and has white rear legs, so I gave it to her a few days before we left for shows, and while we were gone. I let her come in heat once the show was over.

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post #5 of 6 Old 12-23-2013, 08:19 PM
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The cost of marbling would really depend on your vet. I would consider holding off on the Depo. I know its used often in zoo medicine (animals held with opposite sex by design) and in humans as a birth control but it has its risks. In humans, it causes bone marrow suppression with prolonged use. I have heard of mares being downright dangerous during their heat cycle. If she is just a bit well ****ty and annoying but not dangerous I would chalk it up to nature/life.

A marble is at least longer lasting and not a chemical.
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post #6 of 6 Old 12-26-2013, 12:46 PM
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What's the dosage they are giving your mare? My mare was on depo a few years ago, and she was the same...she still showed signs of being in heat, although it was just less drastic than pre-depo.

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