Flunixin and bute by oral - The Horse Forum
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post #1 of 9 Old 06-23-2019, 08:54 AM Thread Starter
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Flunixin and bute by oral

Hi , I live in India with very limited access to equine vets and equine specific meds. Has anyone used the flunixin and bute formulated for IV administration by oral or sublingual routes. If it is possible, It would help me immensely as i don't have access to the oral formulations. Please advice.
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post #2 of 9 Old 06-23-2019, 10:17 AM
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Carriers are different and formulations as well as dosing levels would be different. Not something I would suggest. Having several nurses in the family I have heard about mistakes where the oral (dosed by single use oral syringe) was given I.V. as they just forced the syringe into the port. While there were some instances that there were no issue except dosage being off there have been issues because the carrier for the med which is not intended to be I.V. caused serious medical emergencies.
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post #3 of 9 Old 06-23-2019, 10:45 AM
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Sorry had to tend to something. I would expect for the opposite you would have to know how the drug is broken down by the G.I. tract as that could effect dosing level and if it is a med that has to be protected through the stomach or stomach acid would destroy it rendering it ineffective or sent to the liver prior to entering bloods and broken down there in a form or level that is ineffective or not as effective. It could also cause harm to the mucosa if it is a drug that has to be buffered to protect those membranes that may not be buffered for I.V. usage. Talk to your vet. The only drug I have had experience with using the I.M. form for oral is banamine (flunixin) and it was under the vets direction and dosage instructions to compensate for the change in route of administration. It was a draft I was using it on and they metabolize differently.


Bute is very caustic and I would expect prepared differently for each route. Not a chance I would take without talking to the vet first.
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Last edited by QtrBel; 06-23-2019 at 10:50 AM.
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post #4 of 9 Old 06-23-2019, 10:55 AM
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I found this on a website called Horse Side Vet Guide.


"Bute is somewhat less effective than Banamine® at controlling abdominal pain (colic) but can still be useful.Non-veterinarians should not use the injectable form of this drug. It is for intravenous use only, and must never be given in the muscle. It is severely damaging to tissues if even a small amount escapes the vein during injection. Severe swelling develops and the tissue may even die and slough out, leaving a huge open wound that can take months to heal."


I suspect if you used it orally you'd cause a burn that would be horrible. As they are both NSAIDs I'd also be concerned giving them together (as in close to the same time where one has not worn off before giving the other).
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post #5 of 9 Old 06-23-2019, 11:13 AM
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It's quite common to use IV flunixin orally. Onset is slower, but low risk.

Bute is a different story. Only use IV for IV. I don't think I've ever seen a vet give IV to an owner, only oral preparations.

Don't give either IM. Bad things happen.
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post #6 of 9 Old 06-23-2019, 12:46 PM
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Originally Posted by ApuetsoT View Post
Don't give either IM. Bad things happen.
For reference, this is what bad things are. Never give banamine IM. I have heard some people do and never had a problem. It's definitely not a risk I would ever take.
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post #7 of 9 Old 06-23-2019, 02:25 PM
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Injectables can be given orally. It's not ideal but if that's your only option the yes. I've never even seen injectable bute. As said, don't do IM.

Do you not know how to do shots? It may be more beneficial to just learn to do shots, it's much easier then it seems!
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post #8 of 9 Old 06-24-2019, 12:42 AM
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You can use the Banamine (Flunixin) orally and it's onset is almost as quick as if you gave it IV. I just squirt some over their grain and have never had a horse refuse it. I rarely use Bute anymore, but do give it IV, not oral route, for one thing it tastes NASTY. If you're willing to learn and your vet is willing to teach you, I'd have the vet teach me to give Banamine IV as it was designed. If you're squeamish or not confident that you can do an IV, stick with oral.

You definitely don't give these meds IM. If the horse gets Clostridium (C. Difficile) it is a nightmare for both the horse and the owner. Can be antibiotic resistant and just takes forever to clear up and leaves a nasty scar when you're done.
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post #9 of 9 Old 07-01-2019, 11:55 PM Thread Starter
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Thank you very much
I appreciate your feedback.
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