Regumate or something else - The Horse Forum
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post #1 of 7 Old 06-17-2019, 08:32 AM Thread Starter
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Regumate or something else

My mare has been on regumate since early February. She had been having intermittent behavior and stiffness issues that after seeing several vets could not be attributed to any lameness issues. (Xrays of stifle, hock, fetlock, etc all clean) So we decided to see if it was a cycle related issue and try regumate. We haven't had any issues and she's been a very good girl. However, last week I noticed she was completely bagged up and full of milk. She is not in pain, she lets me touch her udder and it is not hot. She also has edema in front of the udder and some back soreness/stiffness. Has anyone else had this happen from Regumate or do you think this is totally unrelated. I am tempted to stop the Regumate and let her have a cycle but I'm afraid she will be horrible to deal with for this first cycle.
Any thoughts? Nothing else has changed in her life. Same feed, same routine.
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post #2 of 7 Old 06-17-2019, 10:33 AM
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We used to have two of our mares on Regumate for different reasons, when we tried the generic form of it one year both mares started lactating, when they went back on the Regumate it stopped.
I don't know why it happened as the two versions are supposed to be identical.


A couple of years ago we put all of our horses on a magnesium supplement through the winter and come spring neither of the two mares that are usually a problem showed any signs of needing to start on the Regumate.
That's continued the same ever since, they have the magnesium every day and we've never needed to use the Regumate again.
I'm normally very skeptical about anything like this but it worked for our horses so I'd always suggest someone with overly hormonal mares give it a try
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post #3 of 7 Old 06-17-2019, 10:40 AM Thread Starter
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that's interesting. she is on the generic "ovamed" not the name brand regumate.
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post #4 of 7 Old 06-17-2019, 10:49 AM
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I can't remember the name of the generic one we had but Ovamed isn't ringing any bells, it might have been Altren.
Our vet couldn't offer any explanation.


I have them on MVP Magnesium 5000 now, I get it through Amazon because it gives me free delivery.
The one mare used to go between attacking the other mares and being 'overly affectionate' with them, either way they didn't appreciate her attitude. She was also very clingy to the other horses when in heat.
The other mare used to hurl herself against the barn wall and make ear piercing squealing noises as well as harassing the others. She was a little edgy to ride when she was in heat too, prone to being stupidly spooky and over reactive.
All this has stopped on the supplement

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post #5 of 7 Old 06-17-2019, 11:59 PM
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Fascinating about the lactating! I too was wondering about nutrition & supping magnesium, as deficiency of this commonly causes stiffness. ...In the mind, not just the body!

Some info I've found helpful; [COLOR=Lime][B]www.horseforum.com/horse-health/hoof-lameness-info-horse-owners-89836/
For taking critique pics; [COLOR=Lime][B]https://www.horseforum.com/members/41...res-128437.jpg
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post #6 of 7 Old 06-22-2019, 11:53 AM
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For many of these off brand drugs, the formula used is comprised of a different isomer (same formula - different arrangement of the atoms). Technically the same but different. An interesting note is that they have found side effects are not the same depending on the isomer used. One of the popular allergy meds for humans that has several generics on the market had one of those generics become the goto when it was discovered that the generic form had fewer and less serious SE than the name brand or other generics.
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post #7 of 7 Old 06-23-2019, 06:19 AM
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Its interesting she's lactating, since regumate (and variations there of) are progesterone supplements. Progesterone suppresses milk production, but does encourage mammary development in mid/late gestation. Wonder if there is a link there?
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