Join Date: Jan 2012
Location: Calgary, AB, Canada
That very much depends on your location and what you want to do with your mare (e.g. do you want to breed her? Go to shows with her? How old is she?)
The basics I would give every horse in North America are Western Equine Encephalitis (WEE), Eastern Equine Encephalitis (EEE) ans Venezuela Equine Encephalitis (VEE) (= 3-way), as well as Tetanus and West Nile Virus (WNV).
Optional are Equine Influenzavirus (Flu)/and Equine Herpesvirus (EHV-1/4, Rhino/Abortion), although neither of them are particularly good vaccines.
Influenzaviruses recombinate a lot, so every Influenzavirus vaccine is a bit of guesswork whether it covers the currently circulating strains.
Herpesviruses are notoriously difficult to vaccinate against, and also very very common. The current herpesvirus vaccines do not protect against neurological manifestations at all, and even the protection against rhino and abortions is mediocre at best.
So if you are on a budget and not breeding your mare, I probably wouldn't bother with those two.
If you are in a region that has a lot of rabies, I would vaccinate for rabies too. That one has to be given by a vet.
Potomac Horse Fever is optional too. The vaccine isn't very good, and it also depends on your location and whether the horses have a lot of water in their pasture.
The last optional one is strangles. Strangles makes sense if you are boarding, or if you take your horse off-property to shows, trail rides, or other events where she has contact with unknown horses. In that case, I would vaccinate for strangles.
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