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Discussion Starter · #1 · (Edited)
So I've heard a LOT of mixed reviews on joint supplements, but the resounding consensus on feed throughs/oral supplements is that they are not as effective as the injectables.

That said, I'd like to spark a discussion on the injectables, which through my research I've found mixed reviews on across the board. My mare had some on and off lameness earlier this year and the vet suggested it was her hocks. We ended up injecting them and she was a million times better! Now that was in March and she's been sound ever since. However more recently she's definitely becoming stiffer again, although still not lame. Just less of a "spring in her step", willingness to really come through and work off her hind. Vet recommended one of the IM or IV drugs to extend the hock injections since those are A. expensive and B. invasive so we'd like to keep them at bay as long as possible if we can.

SO what injectable joint drugs have you used with your horse(s) and what's your experience with them? These are the 3 I have frequently heard about...

Adequan
Legend
Polyglycan

He actually recommended a sort of "generic" Polyglycan mix he uses a lot that's slightly different than the brand name version. He's been giving it to her monthly for the past couple months and I THINK it's made a difference, but it hasn't been drastic and I'm wondering if what I am seeing is a placebo in my head anyway :wink: Hence why I am asking on here...it has to be given IV, and I'd like to be able to administer myself if possible, which would mean one of the IM meds more than likely since I don't really want to mess with learning to give IV myself if I can help it (which just leaves Adequan from my little list above I believe). If I can find someone to teach me to give IV I would be willing to learn, but it makes me more nervous than learning IM.

I was going to switch to Adequan just because it's IM and seems to be a common one used, BUT then I started hearing rumors from people about there potentially being a recent finding that was not very positive with this drug...I can't really find any more info on it yet since I guess it's been pretty recent, so I'm looking into that one more before I switch her over to give it a try...so if anyone has any info on that let me know, I'd be interested to learn what the rumors have all been about.
 

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I don't like to compare Adequan and Legend because they each do completely different things in the body- they are quite symbiotic though and many people choose to administer both in their horses joint schedule.

Adequan works on the cartilage in a joint and Legend is hylauronic sodium, a basic component of synovial joint fluid so it aids that and aids with inflammation in the joint capsule.

I'm not too versed on polyglycan so I can't say much about it, but I have heard that it is somewhat similar to Adequan.

~Anebel~ has a lot of knowledge in this area, she can probably give you a very detailed description of these meds.

Good luck!
 

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I use Pentosan. It helps with inflammation as well as joint health, which is why i chose Pentosan over Adequan.

The shots cost me $19 each, which is half the price of others I have looked at. It has done wonders for my mare.
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Discussion Starter · #4 ·
Thanks! I'll have to PM her a message and get her take on it as well...

And my vet told me that this mix he uses that he says is "like" polyglycan...he says it's somewhat of a mix of Adequan and Legend together. I'll have to take a closer look at the bottle when I head to the barn tonight and see exactly what's listed on it.
 

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Discussion Starter · #5 ·
CLaPorte, is that a once a month injection? If so that is a very good price. The "polyglycan" mix my vet uses shakes out to around $25/month and that's not including the administration of it, just the cost of the drug itself.
 

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My mare has pretty moderate arthritis due to an injury.

Now that its winter, there is more swelling due to the cold temps we've been having. we give it to her every 3 weeks. I tried once a month, but she needed it a little more frequently then that. 3 weeks is an adequate schedule for her.

I gave her loading doses (double shot) every week for 3 weeks, then 1 loading dose 2 weeks later, and then I kept her on one 6ml shot every 2 weeks for awhile. (months) and then I went to once a month for a few months and as I started riding more, I moved to every 3 weeks.

I was the first client of my vet's to use Pentosan. and since then, its really become a hit for her.

also, they have a 100ml dose that we are going to start giving to my dog that has a OCD leision. he's 4 now, and our vets have looked at it, and there isnt anything we can do for him now. we caught it too late unfortunately so surgery would be a waste of money as there is too much damage done now.

the equine dose is 250ml.
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I don't have personal experience per say, though I will be hopefully starting my gelding on Adequan soon. But there was a horse at my barn who was basically the poster child for Adequan, you could tell when he was due, then would be right as rain after getting it.
 

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Discussion Starter · #8 ·
Thanks for the info CLaPorte!

SullysRider, you'll have to update me on here and let me know how it goes! My vet also recommends Adequan and I have heard great things about it...but the rumblings going around lately are that supposedly they are in the midst of investigating some bad side effects that have recently shown themselves or something. I can't find any more info on it though, so I'm not really sure how much truth there is to that claim, or whether someone has just stirred up a false alarm rumor.
 

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every horse is an individual. just because Adequan works for some horses, doesnt mean they will work for others. so OP, you may need to try different things before finding what works for your horse.

so if you dont notice a difference, try something else. or try adding an oral supplement to the mix.

Rumor gets Pentosan, pure MSM and CortiFlex with HA. she's 100% sound on this combination...But it took rest and trial and error to find what works for her.
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Discussion Starter · #10 ·
every horse is an individual. just because Adequan works for some horses, doesnt mean they will work for others. so OP, you may need to try different things before finding what works for your horse.

so if you dont notice a difference, try something else. or try adding an oral supplement to the mix.

Rumor gets Pentosan, pure MSM and CortiFlex with HA. she's 100% sound on this combination...But it took rest and trial and error to find what works for her.
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So true! It gets so frustrating sometimes because there are just so many options out there to try!
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Well, this is all good information. I have reiners and that sport is extremely hard on their joints. My last trainer would use Adequan once a month and then right before a show. He used this on all horses, sore or not. If a horse was more likely to be sore or an older horse he would up the dose to 2x a month.

Now, I also have an X racehorse and she has kissing spine, fused spine and bone spurs on her neck (basically she is a wreck) I keep her on SmartPak Senior. It is amazing. I use the powder and mix a small amount of water in with her feed to make the powder stick to food. When she is off it she is sore and stiff and her hind end is awkward. She isn't perfect b/c her body can't move perfectly because her spine is fused, but I see a huge difference. Oh and I am not a sales person for SmartPak, but they do put a lot of research on their products.

I am interested in trying the Pentasan. One of my boarders use a glucosamine shot. there is a loading dose in the beginning, but now I think it's once a week. I don't know about you guys, but glucosamine works wonders for me. LOL.
 

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Subbing. :) Good discussion guys! I may have to add something for Red next year, so all this information is great.
 
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