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My filly has the same thing right now, and just today I started her on sulpha (essentially the same thing as you have). There is n ot a whole lot you can do other than what you are doing. If your horse is coughing even after treatment, you may want to look into and expectorant (like sputolysin), but you didn't mention coughing. It is most likely some kind of rhino virus you can't vax for. If she runs a temp, has laboured breathing etc, be sure to contact your vet.
As for the weight issue...have you ever thought that she may have ulcers?
As for the weight issue...have you ever thought that she may have ulcers?